The transcriptome?wide landscape of molecular subtype?specific <scp>mRNA</scp> expression profiles in acute myeloid leukemia

Molecular classification of acute myeloid leukemia (AML) aids prognostic stratification and clinical management. Our aim in this study is to identify transcriptome-wide mRNAs that are specific each the molecular subtypes AML. We analyzed RNA-sequencing data 955 AML samples from three cohorts, including BeatAML project, Cancer Genome Atlas, a cohort Swedish patients provide comprehensive view subtype-specific mRNA expression. identified 729 mRNAs, discovered project validated other two cohorts. Using unique proteomics data, we also presence at protein level, yielding rich collection potential protein-based biomarkers for community. To enable exploration expression by broader scientific community, an interactive resource public.